GSK would like to have a equipment/device to accurately release HFa134a in linear and consistent rate covering a range of 0.5mg to 40mg per day in order to calibrate existing detection equipment.
Metered Dose Inhalers (pMDI) are used by patients suffering from asthma or other respiratory illnesses. pMDIs contain small aluminum cans of drug suspended in the CFC-free propellant HFa134a (1,1,1,2-Tetrafluoroethane).
Our objective is to continuously improve the quality of our products. For this purpose, we are seeking a solution to accurately release HFA134a at specific and consistent leak rate, to represent a leaking filled pMDI can. The method to release HFa134a will be used to calibrate and check an existing laser based detection equipment.
We are seeking equipment that can represent a HFA134a filled pMDI cans that can leak at specific linear and consistent leakage rate from 0.5-40 mg/day. Target is to have a standard certified to qualify the existing equipment (ensure that calibration is right) and check in routine (// weight standard)
Figure 2 Table capturing the desired benchtop solution performance
GSK is interested in all possible solutions that can meet the requirements.