The Client possesses technology of their own to create peptide compounds that have potent effects on the drug discovery target, and has been carrying out research and development for the creation of new drugs based on a peptide compound. If this proposed project is successful in combining the technology with a formulation or DDS technology that enables the effective delivery into cells of peptides, including those that have poor permeability, it can help further accelerate / evolve the research and development of peptide drugs. The Client has therefore decided to make this RFP to accelerate their peptide drugs research and development through collaboration with a partner who possesses a delivery technology to improve the cell entry ability of peptide compounds discovered in-house.
Note that the Client welcomes a proposal of a technology that has a potential of fulfilling the above-stated requirements in the future, even if it is not applicable to poorly membrane-permeable peptide compounds at present.
Anticipated Project Process
After the submission due date, the client will review all submitted proposals. NineSigma will send the review results to each proposer 6-8 weeks after the due date. The client possibly asks clarifying questions before selecting the most suitable candidates for collaboration. The client will select best candidates through evaluations. Once selected, candidate technology(s) will be validated in a feasibility study, etc. During the selection process, the client may execute non-disclosure agreement (NDA) with selected respondents, seek further information disclosure, and discuss specific development targets or potential opportunities. The client will execute necessary agreements with the selected respondents and move to the advanced development phase. Specifics of any collaboration will be determined through consultation with the concerned parties.
Proposal shall have clear points and should not include confidential information. Supplemental files may be submitted in addition to the proposal.
The client will evaluate all responses with the following criteria.
- Overall scientific and technical merit
- Approach to proof of concept or performance
- Economic potential of concept
- Realism of the proposed plan (action items, timeline, roles, deliverables, cost estimation)
- Potential for proprietary position
- Respondents’ capability and related experiences