The client, Daiichi Sankyo Co., Ltd., is engaged in the development of drugs targeting cancer-associated fibroblast (CAF). Because CAF, one of the interstitial cells observed in many types of solid tumors, promotes cancer development by mutually interacting with tumor tissue, CAF-targeted therapies are actively promoted.
To evaluate CAF-targeted drugs appropriately, assay system derived from a clinical sample, in which the interaction between human CAF and human cancer cells can be accurately reflected, need to be established. However, the client has yet to establish appropriate assay system due to problems in accessing and handling clinical samples.
Therefore, the client has issued this open request so as to discover a potential partner for collaboration in establishing assay system and evaluating the drug.
Please describe the content of the proposal, focusing on the main requirements, and do not include confidential information. Please attach reference materials if necessary.
Evaluations for all proposals received will be performed by the client. The proposal is evaluated according to the following evaluation criteria.
- Overview of the proposal/organization
- Feasibility of fulfilling the target specifications
- Economic feasibility
- Potential ownership (exclusive rights, priority, etc.)
- Related achievements
Anticipated Project Process
Respondents are required to submit proposals using the template.
The client will first perform a primary application screening for approximately 6–8 weeks. Additional questions and direct discussions will be given to promising proposals, and candidates will be selected for the final selection. In the selection process, the respondent and the client will conclude a non-disclosure agreement (NDA) as necessary to discuss further information disclosure and detailed development procedures.
After that, the client will conclude the necessary contracts with the respondent to establish the technology by demonstrating and developing the technology. The specific collaborative business framework will be determined through discussion.