Request for Proposal
Status: RFP is Closed

Food Ingredient with Stimulatory Effect other than Caffeine

Request Number
Due Date
Dec 8, 2018
Program Manager

Contract research, joint development, supplier agreement

Phase 1 – Selection of the partner: in a half year
Phase 2 – Investigation on mass-production: starting in 2 years (after Phase 1)

Necessary development expense will be covered
(Details to be discussed).

How to  Apply
  • Click on "Respond", complete the form to the extent possible, and submit along with other attachment files available. 
  • After creating your account for NineSights, your draft will be automatically saved and you can resume later from "Control Center". Please note you do not submit confidential information at this process.
  • This request for proposals in PDF format is available here.


If you have any questions or request, please feel free to contact us at:
RFP was closed on
Dec 2018

RFP Title


Food  Ingredient with Stimulatory Effect other than Caffeine
RFP Description

NineSigma, representing a multi-billion-dollar global beverage manufacturer, seeks a food ingredient with a stimulatory effect other than caffeine.

The sought food ingredient should have a stimulatory effect or an effect to prevent sleepiness or to clear the head; however, clear scientific evidence is not necessarily required at this point. The client intends to select a potential ingredient through sample testing.

Key Success Criteria

Requirements of Requested Food Ingredient

  • The ingredient should have a stimulatory effect or effect to prevent sleepiness or to clear the head.
    • It is preferable that scientific evidence exists; however, if not, the effect can be evaluated via a study conducted by the client.
    • Proposals based on information locally passed on, such as traditional knowledge, are also welcome.
  • The ingredient should be applicable to a food or beverage. (It should be considered safe for humans to take on a daily basis.)
  • In the case of a mixed ingredient, it is not necessary at this point that the active compound or mechanism has been identified.
  • The provision of a sample should be possible. (100 g or more; the cost may be covered by the client.)
Items to be Submitted


While caffeine is known to have a stimulatory effect and to be highly effective in improving concentration and endurance, its disadvantages has been pointed out, e.g. health damage caused by excessive intake.

In order to contribute to people's health, the client wishes to take advantage of a food/beverage ingredient that has the same benefit as that of caffeine and, at the same time, can be consumed more safely.

Therefore, the client has issued this open request to seek the attention of researchers and organizations around the world to identify a potential matching ingredient and apply it to beverage development that helps improve people’s lives.


Notes on Response

Proposal shall have clear points and should not include confidential information. Supplemental files may be submitted in addition to the proposal.


Response evaluation

The client will evaluate all responses with the following criteria.

  • Overall scientific and technical merit
  • Approach to proof of concept or performance
  • Economic potential of concept
  • Realism of the proposed plan (action items, timeline, roles, deliverables, cost estimation)
  • Potential for proprietary position
  • Respondents’ capability and related experiences


Anticipated Project Process

After reviewing submitted proposals, the client possibly ask clarifying questions before selecting the most suitable candidates for collaboration. The client will select best candidates through evaluations. During the selection process, the client may execute NDA with selected respondents, seek further information disclosure, and discuss specific development targets or potential opportunities.

The client will execute necessary agreements with the selected respondents and move to the advanced development phase. Specifics of any collaboration will be determined through consultation with the concerned parties.

Preferred Collaboration Types
Area of Interest