Contest Number:


Ohio Opioid Technology Challenge Topic 1: Diagnose

Ohio Opioid Technology Challenge - Topic 1 DIAGNOSE : 

Rapidly Identify Individuals at High Risk of Addiction  

The Ohio Opioid Technology Challenge is a three-phase prize competition that seeks to accelerate the development and deployment of innovative technology solutions that address the opioid crisis through addiction prevention and treatment, and overdose avoidance and response. 

The Challenge Phase consists of four Challenge Topics that address specific unmet needs or concerns related to opioid use, abuse and exposure. Topic 1 seeks solutions that rapidly identify individuals at high risk of addiction

Persons become involved with the use of opioids by a variety of pathways—receiving a prescription to address pain after injury or surgery or to manage chronic pain, using illicit drugs, providing patient care as a clinician or first responder.  

One way to address addiction is to understand whether a person who is a candidate to receive an opioid has a predisposition to become an addict.  If a physician could administer a diagnostic to understand the risk for addiction before prescribing opioids, then he/she could consider alternative methods of treatment for those at high risk of addiction.

About the Challenge

NineSigma, on behalf of the State of Ohio, seeks challenge responses which Rapidly Identify Individuals at High Risk of Addiction.

Responses should be solutions already in development, focused specifically on the Topic. Responses could include but are not limited to: physiological or genetic diagnostic technologies, diagnostic questionnaire (paired with novel technology), or analysis algorithms.


The Challenge Phase will conclude by awarding up to twelve (12) $200,000 prizes across the four Topics. Prize Recipients of the Challenge Phase will be eligible to compete in the final, Product Phase of the Challenge with prizes of $1 million or more. 


Success Criteria



Responses should consider:


  • How your approach aligns with Key Attributes for the Topic for which you are submitting an Entry
  • Technology maturity and time to market
    • For similar approaches, preference will be given to the one that is more mature and/or that has a shorter time to market
  • Potential for broad deployment or implementation
  • Size/scope of audience impacted (“market size”)
  • Robustness
  • Effectiveness




Your approach should:


  • Enable identification of a person’s risk of addiction
  • Offer clear interpretation or signaling
  • Offer concrete evidence that demonstrates efficacy
  • Be effective in as short a time as possible
  • Be robust 
    • Have low occurrence of false events
  • Be easy to implement and use (from a patient  and/or clinician perspective) 


Download the Challenge Summary for a full description of the Success Criteria.




Must submit a response by July 11, 2018 by 5:00 PM EDT to be eligible.  See the Challenge Official Rules for details.

Challenge Moderator
  • Senior Program Manager
  • NineSigma

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