In the health functional evaluation of proteins, it is a general problem that extrapolation from in vitro evaluation results to in vivo evaluation is low.
This is because effects of the digestion and absorption of protein materials in the body cannot be reflected in in vitro evaluation.
It is hence expected that the extrapolation will be improved by using the pretreatment that mimics the state of digested and absorbed protein materials and subsequently performing in vitro assay.
The Client wants to identify organizations, engineers, or researchers with promising technologies that can solve the problems as soon as possible, and hence decided to recruit technology proposals.
Proposal shall have clear points and should not include confidential information. Supplemental files may be submitted in addition to the proposal.
The client will evaluate all responses with the following criteria.
- Overall scientific and technical merit
- Approach to proof of concept or performance
- Economic potential of concept
- Realism of the proposed plan (action items, timeline, roles, deliverables, cost estimation)
- Potential for proprietary position
- Respondents’ capability and related experiences
Anticipated Project Process
After the submission due date, the client will review all submitted proposals. NineSigma will send the review results to each proposer 6-8 weeks after the due date. The client possibly asks clarifying questions before selecting the most suitable candidates for collaboration. The client will select best candidates through evaluations. During the selection process, the client may execute NDA with selected respondents, seek further information disclosure, and discuss specific development targets or potential opportunities.
The client will execute necessary agreements with the selected respondents and move to the advanced development phase. Specifics of any collaboration will be determined through consultation with the concerned parties.