Synthesis of Highly Water-Reactive Arsenic Compound

Request Number REQ6339713
Due Date April 6, 2017
Author Seh-Rin Sung
Request for Proposal Details
RFP Title
Synthesis of Highly Water-Reactive Arsenic Compound
RFP Description

NineSigma, representing a global chemicals manufacturer, seeks a technology to synthesize a highly water-reactive arsenic compound that can be hydrolyzed.


The client has been working on the development of a hydrolysable arsenic compound. However, this type of compound is very difficult to synthesize or produce in a stable manner, because it is extremely reactive with water, even with a small amount of moisture present in the local environment.


Therefore, the client has issued this open request in order to solve this problem and to quickly establish a promising technology with an organization having experience in synthetic reaction under water-prohibitive conditions.


Anticipated proposals are from organizations that have experience or knowledge about synthesis reaction under water-prohibitive conditions. (Proposals at a concept level are also welcome.)


Key Success Criteria

Requirements for the anticipated technology

  • Compounds to be synthesized:
    • Trivalent or pentavalent arsenic compounds having the following functional groups
      • -OR (e.g., R’nAs(OR)3-n n=0~2)
      • -NR2 (e.g., R’nAs(NR2)3-n n=0~2)
    • Arsenic compounds presumed to be hydrolysable other than the compounds listed above (functional groups are not  specified)
  • Purity: 90% or more


Since the compound sought in this request is highly unique, proposals that will likely enable synthesis of arsenic compounds in principle are widely welcomed, regardless of productivity. (Proposals at a concept level are also welcome.)



Possible Approaches

  • Organization that has a track record in the synthesis or production of the target compound
  • Organization that has knowledge about the following technologies and is willing to jointly develop, with the client, a synthesis technology of the target compound
    • Synthesis of inorganic and organic arsenic compounds
    • Synthetic process that needs to be performed under water-prohibitive conditions


Preferred Collaboration types
  • Joint Development
  • Technology Licensing
Items to be submitted

Anticipated Project Phases or Project Plan

Respondents should submit proposals using the attached Response Template. The client will review submitted proposals and possibly ask clarifying questions before selecting the most suitable candidates for collaboration. The client will select the best candidate(s) through evaluations. During the selection process, the client may execute non-disclosure agreements (NDA) with selected respondent(s), seek further information disclosure, and discuss specific development targets or potential opportunities.

The client will execute necessary agreement(s) with the selected respondent(s) and move to the project execution phase. Specifics of any collaboration will be determined through consultation with the concerned parties. The assumed period would be 1 year for technology development and 1-2 years for scale-up for mass production.



Items to be Included in the Proposal

Responses will use the Proposal Template which is linked to the “attachments“ shown at the bottom of the link <REQ6339713> and include the following items:


  • Overview of the proposed technology
  • Development stage (Concept level/Performance verified in lab /Implemented to practical use)
  • Current performance regarding the arsenic compound
    • Starting material
    • Synthetic route
    • Compound to be synthesized and its purity (%)
    • Scale of synthesis (g) and yield (%)
  • Experience and knowledge about purification of arsenic compounds (e.g. method to reduce metal impurity levels in the product)
  • Development plans to achieve the goal required by the client
  • Any requests concerning the collaboration form (joint development/contract development/technology licensing/others)
  • Past achievements of related synthesis technology (such as research papers and presentations)


Area of Interest
Request Priority